About Orbus Therapeutics, Inc.
Orbus Therapeutics, Inc. is a privately held biopharmaceutical company focused on developing treatments for rare diseases with limited therapeutic options, particularly malignant brain tumors. Founded in 2012, the company’s lead product candidate is oral eflornithine, which has been investigated in combination with lomustine for patients with recurrent anaplastic astrocytoma, a type of brain cancer. Orbus completed its Phase 3 STELLAR clinical study in 2024 and subsequently reported results showing clinically meaningful improvements in overall and progression-free survival in a subgroup of patients with recurrent IDH-mutant grade 3 astrocytoma. The company’s activities include clinical development, regulatory strategy, and commercialization planning for rare-disease therapies